Humoral & Cellular Immunology

Our immune system distinguishes two categories of foreign substances. One category consists of antigens (foreign substances) that are freely circulating in the body. These include molecules, viruses, and foreign cells. The Second Category consists of self-cells that display aberrant MHC(Major Histocompatibility Complex) proteins. These aberrant MHC proteins can originate from antigens that have been engulfed and broken down (exogenous antigens) or from tumor cells and virus‐infected that are actively synthesizing foreign proteins (endogenous antigens).
Depending on the kind of foreign invasion, two different immune responses occur:
The Humoral response (or antibody‐mediated response) involves B cells that pathogens or recognize antigens that are circulating in the lymph or blood (“humor” is a medieval term for body fluid). In this, the antigens bind to B cells which lead to Interleukins or helper T cells stimulate B cells. In most cases, both an antigen and a stimulator are required to activate a B cell and initiate B cell proliferation. Further, B cells proliferate and produce plasma cells. The plasma cells bear antibodies with the identical antigen specificity as the antigen receptors of the activated B cells. The antibodies are released and circulate through the body, binding to antigens. Finally, B cells produce memory cells which provide future immunity.
The Cell‐mediated response involves mostly T-cells and responds to any cell that displays aberrant MHC markers, including cells invaded by pathogens, tumor cells, or transplanted cells. Self-cells or Antigen Presenting Cells (APCs) displaying foreign antigens bind to T cells. The Interleukins (secreted by APCs or helper T cells) stimulate activation of T cells. If endogenous antigens and MHC‐I are displayed on the plasma membrane, T cells proliferate, producing cytotoxic T cells. The Cytotoxic T cells destroy cells displaying the antigens. If exogenous antigens and MHC‐II are displayed on the plasma membrane, T cells proliferate, producing helper T cells. The Helper T cells release interleukins (and other cytokines), which stimulate B cells to produce antibodies that bind to the antigens and stimulate nonspecific agents (NK and macrophages) to destroy the antigens.
 

  • T cells and B cells
  • Adaptive immunity
  • Antigen receptor sites
  • Immunoglobulins
  • Functions of Antibodies
  • Inflammation and Inflammatory factors
  • Complement system
  • Monocytes and Macrophages
  • Non-antibody immunity
  • Resistance to Intracellular Microbial and Viral infection

Related Conference of Humoral & Cellular Immunology

March 04-05, 2019

10th Molecular Immunology & Immunogenetics Congress

Barcelona, Spain
March 18-19, 2019

2nd World Congress on Allergy, Infectious Diseases and Immunology

Sydney, Australia
March 18-19, 2019

11th Global Summit on Immunology and Cell Biology

Sydney, Australia
March 18-19, 2019

13th International Congress on Autoimmunity

Brisbane, Australia
April 15-18, 2019

Annual Immunology Conference 2019

Savannah, USA

Autoimmunity Confernece 2019

June 10-11, 2019

2nd International Conference on Dermatology and Allergic Diseases

Helsinki, Finland

vaccinesresearch-vac-2019

June 13-14, 2019 |

10th European Immunology Conference

Berlin, Germany
June 17-18, 2019

International Conference on Vaccines and Immune Response

Dubai, UAE
July 24-25, 2019

11th World Congress and Expo on Immunology

Vancouver, Canada
July 29-30 2019

6th International Conference on Parasitology & Microbiology

Amsterdam, Netherlands
August 22-23, 2019

11th International Conference on Clinical and Cellular Immunology

Vienna, Austria
August 29-30, 2019

13th International Conference on Allergy, Asthma & Clinical Immunology

Vienna, Austria

Psychoneuroimmunology-2019

September 18-19, 2019

4th Antibodies, Antibiotics and Bio Therapeutics Congress: R&D, Market and B2B

San Francisco, USA
October 21-22, 2019

12th Annual Congress on Immunology & Immunogenetics

Rome, Italy
November 21-22, 2019

14th International Conference on Allergy and Clinical Immunology

Bali, Indonesia
November 22-23, 2019 |

World Conference on Vaccine and Immunology

Dubai, UAE

Humoral & Cellular Immunology Conference Speakers

Recommended Sessions

Related Journals

Are you interested in